chafe -
To be annoyed or lose patience because of rules or limits
Though Ted loved his father (and boss), he chafed under his father's strict supervision, and he was looking forward to the day when his father would retire so he could run the company himself.
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unsettling -
Causing anxiety or uneasiness; disturbing.
She found it quite unsettling that often someone would ring the doorbell and then when she opened the door, there was nobody there.
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frustrating -
Causing feelings of irritation or annoyance due to difficulties, obstacles, and lack of progress.
It’s so frustrating when the internet keeps disconnecting in the middle of an important video call.
adjective
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leery -
Cautious or wary due to realistic suspicions
Ever since she was bitten by a pitbull, Grace was leery of any dog she encountered.
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awkward -
Lacking grace or ease in movement or behavior, especially in social situations.
She felt awkward meeting her ex husband at the party, and they tried to avoid each other as much as possible.
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desperation -
A strong feeling of fear and loss of hope.
Their credit card debt was so large, that they felt a sense of desperation about being able to fix the situation.
adjective
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uneasy -
Feeling anxious, worried, or uncomfortable about something; feeling a sense of discomfort or restlessness.
She felt uneasy walking alone through the dark alley.
verb
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fidget -
To make small movements, especially of the hands and feet, through nervousness or impatience
Ron nervously fidgeted with his hands before giving the speech to 10,000 people.
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jarring -
Causing a sudden, unpleasant, or shocking effect.
The loud and sudden fire alarm was jarring in the otherwise quiet neighborhood.
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harried -
To be busy and annoyed by the demands of others
Jim didn't like being a waiter, because he always felt harried by the demands of all the customers.
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colicky -
Having severe abdominal pain, often caused by spasm, obstruction, or distention of any of the hollow viscera, such as the intestines
Pam's crying baby was colicky because of intestinal problems.
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bumpy -
Unstable or rough, especially describing a ride or journey.
The bike ride was bumpy because of all the potholes.