deranged -
Behaving in an uncontrolled or dangerous way because of mental illness
Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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psycho -
A person with severe mental health issues, often describing someone who behaves in an erratic or dangerous manner.
She accused him of being a psycho and told him to leave after he repeatedly showed up uninvited and acted innappropriately.
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cantankerous -
Bad-tempered, argumentative, and uncooperative
The constant arguing of the cantankerous couple living above Ann always kept her up at night.
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maniac -
Someone who is mentally ill tending towards violent and dangerous behavior.
The film’s villain was portrayed as a ruthless maniac with no regard for human life.
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megalomaniac -
Someone who has an unnaturally strong wish for power and control.
The dictator showed signs of being a megalomaniac even as a child, the way he bossed everyone around in the schoolyard.
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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crackpot -
A slightly strange or foolish person
Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.
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bonkers -
Mentally unbalanced, mad and crazy, usually meant humorously
There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.
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lunacy -
Stupid or crazy ideas or behavior that is likely to have bad results
When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.
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delirious -
In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.
After three sleepless nights, he was delirious and barely able to speak clearly.
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weirdo -
A person whose dress or behavior seems strange
The weirdo kept peeking at everyone from behind the bushes.