disruptive -
Causing problems or preventing something from continuing smoothly.
During class recess, Joey was always disruptive, and the teacher didn't know quite how to handle it.
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loony -
Crazy or silly
The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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crank -
Someone who others think has unusual ideas or behaves strangely
Bill was seen as crank by his friends, because of the way he always spoke of the dangers of eating meat and being vaccinated.
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psycho -
A person with severe mental health issues, often describing someone who behaves in an erratic or dangerous manner.
She accused him of being a psycho and told him to leave after he repeatedly showed up uninvited and acted innappropriately.
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kooky -
Strange and different, in a funny way
Salvador Dali's kooky appearance was only exceeded by his even more bizarre paintings.
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delirious -
In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.
After three sleepless nights, he was delirious and barely able to speak clearly.
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deranged -
Behaving in an uncontrolled or dangerous way because of mental illness
Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs
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zany -
Amusingly unconventional and different
Einstein was unique among geniuses in that he also had a silly and zany side of his personality.
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weirdo -
A person whose dress or behavior seems strange
The weirdo kept peeking at everyone from behind the bushes.
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maniac -
Someone who is mentally ill tending towards violent and dangerous behavior.
The film’s villain was portrayed as a ruthless maniac with no regard for human life.