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cramps - A painful, involuntary contraction of muscles

When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

verb

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writhe - Make continual twisting, squirming movements or contortions of the body

The soccer player writhed in pain on the ground after spraining his ankle.

noun

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agony - Extreme physical or mental suffering

Max was in physical agony as he rode his bicycle up the long mountain trail, but spiritually and emotionally he was in heaven.

noun

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inflammation - A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.

The redness of the big toe was caused by an infection, and the inflammation was visible and painful.

noun

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angst - A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general

Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.

nounverb verb

See noun

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bruise - To hurt someone emotionally or physically, leaving a lasting feeling of pain or vulnerability.

The teacher's harsh words bruised his self-esteem.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

adjective

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excruciating - Intensely painful

Becky had to see the dentist because her toothache was causing her excruciating pain.

nounverb noun

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burden - something you carry or withstand with much difficulty.

Financial debt can be a huge burden on families.

verb

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wince - Give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress

Tiger winced as he realized he had hit the ball too far beyond the hole.

adjective

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humiliated - To feel ashamed after someone embarrasses you in front of others.

When Jim revealed to everyone at the party that Marty hadn't even finished 6th grade, Marty felt humiliated.