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psycho - A person with severe mental health issues, often describing someone who behaves in an erratic or dangerous manner.

She accused him of being a psycho and told him to leave after he repeatedly showed up uninvited and acted innappropriately.

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weirdo - A person whose dress or behavior seems strange

The weirdo kept peeking at everyone from behind the bushes.

adjective

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hysterical - Having uncontrolled extreme emotion

When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.

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loony - Crazy or silly

The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.

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berserk - To behave in a wild and uncontrolled way as a result of something unexpected happening.

When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.

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zany - Amusingly unconventional and different

Einstein was unique among geniuses in that he also had a silly and zany side of his personality.

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kooky - Strange and different, in a funny way

Salvador Dali's kooky appearance was only exceeded by his even more bizarre paintings.

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lunacy - Stupid or crazy ideas or behavior that is likely to have bad results

When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.

adjective

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wacky - Something that is strange and different to the point of amusement.

George’s grandmother was well known and loved for her wacky taste in shoes.

adjective

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delirious - In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.

After three sleepless nights, he was delirious and barely able to speak clearly.

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megalomaniac - Someone who has an unnaturally strong wish for power and control.

The dictator showed signs of being a megalomaniac even as a child, the way he bossed everyone around in the schoolyard.

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bonkers - Mentally unbalanced, mad and crazy, usually meant humorously

There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.